The Skull Man Vol 4

From the Tokyopop edition

The poisonous effects of consumerism have raged unchecked since the advent of the Industrial Age, and now modern society faces a pollution problem of epidemic proportions. And, in this decaying world, one mysterious organization - one entrenched in the field of genetic research - threatens to accelerate the downward spiral of humanity. The Cobra Man has been dispatched as an agent of the organization to make sure everything goes as planned. Tatsuo Kagura (a.k.a. The Skull Man, an ambassador from the world of the dead bestowed with extraordinary abilities, who searches desperately for his parents' killers and the nature of his powers - both somehow linked to the organization) may be the last hope mankind has. But Kagura is torn between his obsession with unlocking the mysteries of his past and his obligation to righteousness. His sister, Maya, a disembodied presence in his life, and Maria, another being with immense power, can help guide him in his quest, if only they can figure out how to funnel their powers of destruction into a form of salvation.

Source: Anime News Network Encyclopedia